O6甲基鸟嘌呤DNA甲基转移酶抗体
产品名称: O6甲基鸟嘌呤DNA甲基转移酶抗体
英文名称: MGMT
产品编号: bs-1002R
产品价格: null
产品产地: 北京
品牌商标: BIOSS
更新时间: 2025-11-17T15:57:36
使用范围: WB=1:100-500,IHC-P=1:100-500,IHC-F=1:100-500,Flow-Cyt=1:100-500,IF=1:100-500,
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市北京经济技术开发区环科中路16号26幢3层301
- 邮编 :
- 所在区域 : 北京
- 电话 : 181****6239 点击查看
- 传真 : 点击查看
- 邮箱 : 3193328036@qq.com
- 二维码 : 点击查看
MGMT (O6 methylguanine DNA methyltransferase) is an enzyme that transfers methyl groups from O(6) methylguanine, and other methylated moities of DNA, to a cysteine residue in itself, thus repairing DNA damage caused by alkylation in a single step reaction. This is a suicide reaction as the enzyme is irreversibly inactivated. MGMT prevents mutagenesis and malignant transformation, and also provides resistance to chemotherapy with alkylating agents among cancer patients.
